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Lipid Composition Regulates the Orientation of Transmembrane Helices in HorA, an ABC Multidrug Transporter

ATP-binding cassette (ABC) transporters constitute a large class of molecular pumps whose central role in chemotherapy resistance has highlighted their clinical relevance. We investigated whether the lipid composition of the membrane affects the function and structure of HorA, a bacterial ABC multid...

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Main Authors: Gustot, Adelin, Smriti, Ruysschaert, Jean-Marie, Mchaourab, Hassane, Govaerts, Cédric
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863179/
https://ncbi.nlm.nih.gov/pubmed/20223819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.079673
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