Dynamics of Haplotype Frequency Change in a CD8+TL Epitope of Simian Immunodeficiency Virus

Deep pyrosequencing of a CD8+TL epitope from the Tat protein of simian immunodeficiency virus (SIV) from four infected rhesus macaques carrying the restricting MHC allele (Mamu-A*01) for that epitope, revealed that natural selection favoring escape mutations led to an increase in the frequency of ha...

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Main Authors: Hughes, Austin L., O’Connor, Shelby, Dudley, Dawn M., Burwitz, Benjamin J., Bimber, Benjamin N., O’Connor, David
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863052/
https://ncbi.nlm.nih.gov/pubmed/20149896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.meegid.2010.02.001
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