Transcriptionally Abundant Major Histocompatibility Complex Class I Alleles Are Fundamental to Nonhuman Primate Simian Immunodeficiency Virus-Specific CD8(+) T Cell Responses

Simian immunodeficiency virus (SIV)-infected macaques are the preferred animal model for human immunodeficiency virus (HIV) vaccines that elicit CD8(+) T cell responses. Unlike humans, whose CD8(+) T cell responses are restricted by a maximum of six HLA class I alleles, macaques express up to 20 dis...

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Autors principals: Budde, Melisa L., Lhost, Jennifer J., Burwitz, Benjamin J., Becker, Ericka A., Burns, Charles M., O'Connor, Shelby L., Karl, Julie A., Wiseman, Roger W., Bimber, Benjamin N., Zhang, Guang Lan, Hildebrand, William, Brusic, Vladimir, O'Connor, David H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2011
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067831/
https://ncbi.nlm.nih.gov/pubmed/21270169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02355-10
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