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Paclitaxel enhances early dendritic cell maturation and function through TLR4 signaling in mice
Subclinical doses of Paclitaxel (PTX) given 1 day prior to a HER-2/neu (neu)-targeted, granulocyte-macrophage colony stimulating factor (GM-CSF)-secreting whole-cell vaccine enhances neu-specific T cell responses and slows neu(+) tumor growth in tolerized HER-2/neu (neu-N) mice. We demonstrate that...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862830/ https://ncbi.nlm.nih.gov/pubmed/20346445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2010.03.001 |
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