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The Combination of MBP and BCG-Induced Dendritic Cell Maturation through TLR2/TLR4 Promotes Th1 Activation In Vitro and Vivo

To explore whether TLR2/TLR4 could be involved in the maturation of dendritic cells and polarization of CD4+ T cells induced by dendritic cells stimulated with MBP and BCG, in vitro and in vivo experiments using TLR2−/− or TLR4−/− mice were employed. MBP and BCG elevated CD80, CD86 and MHC class II...

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Principais autores: LiNa Jiang, GuoMu Liu, WeiHua Ni, NanNan Zhang, Jing Jie, Fei Xie, GuiXiang Tai
格式: Artigo
語言:Inglês
出版: Wiley 2017-01-01
叢編:Mediators of Inflammation
在線閱讀:http://dx.doi.org/10.1155/2017/1953680
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