A Phase I Trial of Repeated Intrapleural Adenoviral-mediated Interferon-β Gene Transfer for Mesothelioma and Metastatic Pleural Effusions

We previously showed that a single intrapleural dose of an adenoviral vector expressing interferon-β (Ad.IFN-β) in patients with malignant pleural mesothelioma (MPM) or malignant pleural effusions (MPE) resulted in gene transfer, humoral antitumor immune responses, and anecdotal clinical responses m...

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Dades bibliogràfiques
Autors principals: Sterman, Daniel H, Recio, Adri, Haas, Andrew R, Vachani, Anil, Katz, Sharyn I, Gillespie, Colin T, Cheng, Guanjun, Sun, Jing, Moon, Edmund, Pereira, Luana, Wang, Xinzhong, Heitjan, Daniel F, Litzky, Leslie, June, Carl H, Vonderheide, Robert H, Carroll, Richard G, Albelda, Steven M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862532/
https://ncbi.nlm.nih.gov/pubmed/20068553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.309
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