A Phase I Trial of Repeated Intrapleural Adenoviral-mediated Interferon-β Gene Transfer for Mesothelioma and Metastatic Pleural Effusions

We previously showed that a single intrapleural dose of an adenoviral vector expressing interferon-β (Ad.IFN-β) in patients with malignant pleural mesothelioma (MPM) or malignant pleural effusions (MPE) resulted in gene transfer, humoral antitumor immune responses, and anecdotal clinical responses m...

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Detalhes bibliográficos
Main Authors: Sterman, Daniel H, Recio, Adri, Haas, Andrew R, Vachani, Anil, Katz, Sharyn I, Gillespie, Colin T, Cheng, Guanjun, Sun, Jing, Moon, Edmund, Pereira, Luana, Wang, Xinzhong, Heitjan, Daniel F, Litzky, Leslie, June, Carl H, Vonderheide, Robert H, Carroll, Richard G, Albelda, Steven M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862532/
https://ncbi.nlm.nih.gov/pubmed/20068553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.309
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