A Trial of Intrapleural Adenoviral-mediated Interferon-α2b Gene Transfer for Malignant Pleural Mesothelioma

New therapeutic strategies are needed for malignant pleural mesothelioma (MPM). We conducted a single-center, open-label, nonrandomized, pilot and feasibility trial using two intrapleural doses of an adenoviral vector encoding human IFN-α (Ad.IFN-α2b). Nine subjects were enrolled at two dose levels....

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Detalhes bibliográficos
Main Authors: Sterman, Daniel H., Haas, Andrew, Moon, Edmund, Recio, Adriana, Schwed, Daniel, Vachani, Anil, Katz, Sharyn I., Gillespie, Colin T., Cheng, Guanjun, Sun, Jing, Papasavvas, Emmanouil, Montaner, Luis J., Heitjan, Daniel F., Litzky, Leslie, Friedberg, Joseph, Culligan, Melissa, June, Carl H., Carroll, Richard G., Albelda, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262033/
https://ncbi.nlm.nih.gov/pubmed/21642245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201103-0554CR
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