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HIV integration site distributions in resting and activated CD4(+) T cells infected in culture

OBJECTIVE: The goal of this study was to investigate whether the location of HIV integration differs in resting versus activated T cells, a feature that could contribute to the formation of latent viral reservoirs via effects on integration targeting. DESIGN: Primary resting or activated CD4(+) T ce...

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Détails bibliographiques
Auteurs principaux: Brady, Troy, Agosto, Luis M., Malani, Nirav, Berry, Charles C., O'Doherty, Una, Bushman, Frederic
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862484/
https://ncbi.nlm.nih.gov/pubmed/19550285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e32832caf28
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