Directly Infected Resting CD4+T Cells Can Produce HIV Gag without Spreading Infection in a Model of HIV Latency

Despite the effectiveness of highly active antiretroviral therapy (HAART) in treating individuals infected with HIV, HAART is not a cure. A latent reservoir, composed mainly of resting CD4+T cells, drives viral rebound once therapy is stopped. Understanding the formation and maintenance of latently...

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Detalhes bibliográficos
Main Authors: Pace, Matthew J., Graf, Erin H., Agosto, Luis M., Mexas, Angela M., Male, Frances, Brady, Troy, Bushman, Frederic D., O'Doherty, Una
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406090/
https://ncbi.nlm.nih.gov/pubmed/22911005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002818
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