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Patients on HAART often have an excess of unintegrated HIV DNA: implications for monitoring reservoirs

HIV establishes a latent reservoir early in infection that is resistant to anti-retroviral therapy and has a slow rate of decay. It is thought that the majority of HIV DNA in treated patients is integrated since unintegrated HIV DNA appears to be unstable. Thus, to monitor the HIV latent reservoir,...

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Détails bibliographiques
Auteurs principaux: Agosto, Luis M., Liszewski, Megan K., Mexas, Angela, Graf, Erin, Pace, Matthew, Yu, Jianqing J., Bhandoola, Avinash, O’Doherty, Una
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253773/
https://ncbi.nlm.nih.gov/pubmed/20970154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.08.024
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