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Patients on HAART often have an excess of unintegrated HIV DNA: implications for monitoring reservoirs

HIV establishes a latent reservoir early in infection that is resistant to anti-retroviral therapy and has a slow rate of decay. It is thought that the majority of HIV DNA in treated patients is integrated since unintegrated HIV DNA appears to be unstable. Thus, to monitor the HIV latent reservoir,...

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Detalhes bibliográficos
Main Authors: Agosto, Luis M., Liszewski, Megan K., Mexas, Angela, Graf, Erin, Pace, Matthew, Yu, Jianqing J., Bhandoola, Avinash, O’Doherty, Una
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253773/
https://ncbi.nlm.nih.gov/pubmed/20970154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.08.024
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