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HIV 2-Long Terminal Repeat Circular DNA is Stable in Primary CD4+ T Cells

Treatment resistant latent reservoirs remain a barrier to curing HIV, but the maintenance and properties of these reservoirs are not completely understood. 2-LTR circular HIV DNA has been used to assess ongoing viral replication in HAART treated patients. However, the half-life of this DNA form is s...

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Detalhes bibliográficos
Main Authors: Pace, Matthew J, Graf, Erin H., O’Doherty, Una
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983779/
https://ncbi.nlm.nih.gov/pubmed/23537959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.02.028
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