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Leptin Reduces Pathology and Improves Memory in a Transgenic Mouse Model of Alzheimer’s Disease

We have previously reported anti-amyloidogenic effects of leptin using in vitro and in vivo models and, more recently, demonstrated the ability of leptin to reduce tau phosphorylation in neuronal cells. The present study examined the efficacy of leptin in ameliorating the Alzheimer’s disease (AD)-li...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Greco, Steven J., Bryan, Kathryn J., Sarkar, Sraboni, Zhu, Xiongwei, Smith, Mark A., Ashford, J. Wesson, Johnston, Jane M., Tezapsidis, Nikolaos, Casadesus, Gemma
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862270/
https://ncbi.nlm.nih.gov/pubmed/20308782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-1308
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