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Leptin Reduces Pathology and Improves Memory in a Transgenic Mouse Model of Alzheimer’s Disease

We have previously reported anti-amyloidogenic effects of leptin using in vitro and in vivo models and, more recently, demonstrated the ability of leptin to reduce tau phosphorylation in neuronal cells. The present study examined the efficacy of leptin in ameliorating the Alzheimer’s disease (AD)-li...

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Detalhes bibliográficos
Main Authors: Greco, Steven J., Bryan, Kathryn J., Sarkar, Sraboni, Zhu, Xiongwei, Smith, Mark A., Ashford, J. Wesson, Johnston, Jane M., Tezapsidis, Nikolaos, Casadesus, Gemma
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862270/
https://ncbi.nlm.nih.gov/pubmed/20308782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-1308
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