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Leptin Inhibits Glycogen Synthase Kinase-3β to Prevent Tau Phosphorylation in Neuronal Cells
We have previously demonstrated that Leptin reduces extracellular amyloid β (Aβ) protein both in vitro and in vivo, and intracellular tau phosphorylation in vitro. Further, we have shown that these effects are dependent on activation of AMP-activated protein kinase (AMPK) in vitro. Herein, we invest...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2681253/ https://ncbi.nlm.nih.gov/pubmed/19429119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2009.03.066 |
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