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Leptin regulates Tau phosphorylation and Amyloid through AMPK in Neuronal Cells

Leptin, which serves as a lipid-modulating hormone to control metabolic energy availability, is decreased in Alzheimer’s disease (AD) patients, and serum levels are inversely correlated to severity of dementia. We have previously described the effects of leptin in reducing amyloid β protein both in...

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Detalles Bibliográficos
Main Authors: Greco, Steven J., Sarkar, Sraboni, Johnston, Jane M., Tezapsidis, Nikolaos
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657956/
https://ncbi.nlm.nih.gov/pubmed/19166821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.01.041
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