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Resonance Raman Studies of the (His)(Cys)(3) 2Fe-2S Cluster of MitoNEET: Comparison to the (Cys)(4) Mutant and Implications of the Effects of pH on the Labile Metal Center

MitoNEET is a 2Fe-2S outer mitochondrial membrane protein that was initially identified as a target for anti-diabetic drugs. It exhibits a novel protein fold, and in contrast to other 2Fe-2S proteins such as Rieske proteins and ferredoxins, the metal clusters in the mitoNEET homodimer are each coord...

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Autores principales: Tirrell, Timothy F., Paddock, Mark L., Conlan, Andrea R., Smoll, Eric J., Nechushtai, Rachel, Jennings, Patricia A., Kim, Judy E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861891/
https://ncbi.nlm.nih.gov/pubmed/19388667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900028r
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