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Planarian Hh signaling regulates regeneration polarity and links Hh pathway evolution to cilia

The Hedgehog (Hh) signaling pathway plays multiple essential roles during metazoan development, homeostasis, and disease. Although core protein components are highly conserved, the variations in Hh signal transduction mechanisms exhibited by existing model systems (Drosophila, fish, and mammals) are...

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Bibliografiske detaljer
Main Authors: Rink, Jochen C., Gurley, Kyle A., Elliott, Sarah A., Alvarado, Alejandro Sánchez
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861735/
https://ncbi.nlm.nih.gov/pubmed/19933103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1178712
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