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Planarian Hh signaling regulates regeneration polarity and links Hh pathway evolution to cilia

The Hedgehog (Hh) signaling pathway plays multiple essential roles during metazoan development, homeostasis, and disease. Although core protein components are highly conserved, the variations in Hh signal transduction mechanisms exhibited by existing model systems (Drosophila, fish, and mammals) are...

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Autors principals: Rink, Jochen C., Gurley, Kyle A., Elliott, Sarah A., Alvarado, Alejandro Sánchez
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861735/
https://ncbi.nlm.nih.gov/pubmed/19933103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1178712
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