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Planarian Hh signaling regulates regeneration polarity and links Hh pathway evolution to cilia

The Hedgehog (Hh) signaling pathway plays multiple essential roles during metazoan development, homeostasis, and disease. Although core protein components are highly conserved, the variations in Hh signal transduction mechanisms exhibited by existing model systems (Drosophila, fish, and mammals) are...

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Detalhes bibliográficos
Main Authors: Rink, Jochen C., Gurley, Kyle A., Elliott, Sarah A., Alvarado, Alejandro Sánchez
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861735/
https://ncbi.nlm.nih.gov/pubmed/19933103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1178712
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