Investigation of PARP-1, PARP-2, and PARG interactomes by affinity-purification mass spectrometry

BACKGROUND: Poly(ADP-ribose) polymerases (PARPs) catalyze the formation of poly(ADP-ribose) (pADPr), a post-translational modification involved in several important biological processes, namely surveillance of genome integrity, cell cycle progression, initiation of the DNA damage response, apoptosis...

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Bibliografiska uppgifter
Huvudupphovsmän: Isabelle, Maxim, Moreel, Xavier, Gagné, Jean-Philippe, Rouleau, Michèle, Ethier, Chantal, Gagné, Pierre, Hendzel, Michael J, Poirier, Guy G
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2010
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861645/
https://ncbi.nlm.nih.gov/pubmed/20388209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5956-8-22
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