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Characterization and development of novel small-molecules inhibiting GSK3 and activating Wnt signaling
Glycogen synthase kinase 3 (GSK3) is an essential component of the Wnt signaling pathway and plays important roles in regulating cell proliferation, differentiation, and apoptosis. As GSK3 is abnormally upregulated in several diseases including type II diabetes, Alzheimer’s disease and cancer, it ha...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2861480/ https://ncbi.nlm.nih.gov/pubmed/19823752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b905752h |
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