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Characterization and development of novel small-molecules inhibiting GSK3 and activating Wnt signaling

Glycogen synthase kinase 3 (GSK3) is an essential component of the Wnt signaling pathway and plays important roles in regulating cell proliferation, differentiation, and apoptosis. As GSK3 is abnormally upregulated in several diseases including type II diabetes, Alzheimer’s disease and cancer, it ha...

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Bibliografische gegevens
Hoofdauteurs: Zhong, Hanbing, Zou, Haixia, Semenov, Mikhail V., Moshinsky, Deborah, He, Xi, Huang, Haigen, Li, Song, Quan, Junmin, Yang, Zhen, Lin, Shuo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861480/
https://ncbi.nlm.nih.gov/pubmed/19823752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b905752h
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