Purified TPC Isoforms Form NAADP Receptors with Distinct Roles for Ca(2+) Signaling and Endolysosomal Trafficking

Intracellular Ca(2+) signals constitute key elements in signal transduction. Of the three major Ca(2+) mobilizing messengers described, the most potent, nicotinic acid adenine dinucleotide phosphate (NAADP) is the least well understood in terms of its molecular targets [1]. Recently, we showed that...

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Autori principali: Ruas, Margarida, Rietdorf, Katja, Arredouani, Abdelilah, Davis, Lianne C., Lloyd-Evans, Emyr, Koegel, Heidi, Funnell, Timothy M., Morgan, Anthony J., Ward, John A., Watanabe, Keiko, Cheng, Xiaotong, Churchill, Grant C., Zhu, Michael X., Platt, Frances M., Wessel, Gary M., Parrington, John, Galione, Antony
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861162/
https://ncbi.nlm.nih.gov/pubmed/20346675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.02.049
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