TPC2 Proteins Mediate Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)- and Agonist-evoked Contractions of Smooth Muscle

Agonists such as those acting at muscarinic receptors are thought to induce contraction of smooth muscle primarily through inositol 1,4,5-trisphosphate production and release of Ca(2+) from sarcoplasmic reticulum. However, the additional Ca(2+)-mobilizing messengers cyclic adenosine diphosphate ribo...

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Bibliographic Details
Main Authors: Tugba Durlu-Kandilci, Nezahat, Ruas, Margarida, Chuang, Kai-Ting, Brading, Alison, Parrington, John, Galione, Antony
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915728/
https://ncbi.nlm.nih.gov/pubmed/20547763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.129833
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