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The Critical Role of AKT2 in Hepatic Steatosis Induced by PTEN Loss

Insulin signaling in the liver leads to accumulation of phosphatidylinositol (3,4,5)-trisphosphate (PIP(3)). Deletion of the phosphatase Pten (phosphatase and tensin homologue deleted on chromosome 10) reduces PIP(3) levels and leads to fatty liver development. The purpose of this study was to inves...

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書誌詳細
主要な著者: He, Lina, Hou, Xiaogang, Kanel, Gary, Zeng, Ni, Galicia, Vivian, Wang, Ying, Yang, Jian, Wu, Hong, Birnbaum, Morris J., Stiles, Bangyan L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Investigative Pathology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861095/
https://ncbi.nlm.nih.gov/pubmed/20348245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090931
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