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The Critical Role of AKT2 in Hepatic Steatosis Induced by PTEN Loss
Insulin signaling in the liver leads to accumulation of phosphatidylinositol (3,4,5)-trisphosphate (PIP(3)). Deletion of the phosphatase Pten (phosphatase and tensin homologue deleted on chromosome 10) reduces PIP(3) levels and leads to fatty liver development. The purpose of this study was to inves...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Investigative Pathology
2010
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2861095/ https://ncbi.nlm.nih.gov/pubmed/20348245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090931 |
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