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Adaptive basal phosphorylation of eIF2α is responsible for resistance to cellular stress induced cell death in Pten null hepatocytes

The α-subunit of eukaryotic initiation factor 2 (eIF2α) is a key translation regulator that plays an important role in cellular stress responses. In the present study, we investigated how eIF2α phosphorylation can be regulated by a tumor suppressor PTEN (phosphatase and tensin homologue deleted on c...

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Podrobná bibliografie
Vydáno v:Mol Cancer Res
Hlavní autoři: Zeng, Ni, Li, Yang, He, Lina, Xu, Xiaoling, Galicia, Vivian, Deng, Chuxia, Stiles, Bangyan L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351767/
https://ncbi.nlm.nih.gov/pubmed/22009178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-11-0299
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