A Parenteral DNA vaccine protects against pneumonic plague

The chemokine, lymphotactin (LTN), was tested as a molecular adjuvant using bicistronic DNA vaccines encoding the protective Yersinia capsular (F1) antigen and virulence antigen (V-Ag) as a F1-V fusion protein. The LTN-encoding F1-V or V-Ag vaccines were given by the intranasal (i.n.) or intramuscul...

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Autores principales: Yamanaka, Hitoki, Hoyt, Teri, Yang, Xinghong, Bowen, Richard, Golden, Sarah, Crist, Kathryn, Becker, Todd, Maddaloni, Massimo, Pascual, David W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861050/
https://ncbi.nlm.nih.gov/pubmed/20197132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.02.022
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