An IL-12 DNA vaccine co-expressing Yersinia pestis antigens protects against pneumonic plague

Pneumonic plague remains problematic in endemic areas, and because it can be readily transmitted and has high mortality, the development of efficacious vaccines is warranted. To test whether stimulation of cell-mediated immunity with IL-12 will improve protective immunity against plague, we construc...

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Bibliographic Details
Main Authors: Yamanaka, Hitoki, Hoyt, Teri, Bowen, Richard, Yang, Xinghong, Crist, Kathryn, Golden, Sarah, Maddaloni, Massimo, Pascual, David W.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628569/
https://ncbi.nlm.nih.gov/pubmed/18955097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.10.021
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