An IL-12 DNA vaccine co-expressing Yersinia pestis antigens protects against pneumonic plague

Pneumonic plague remains problematic in endemic areas, and because it can be readily transmitted and has high mortality, the development of efficacious vaccines is warranted. To test whether stimulation of cell-mediated immunity with IL-12 will improve protective immunity against plague, we construc...

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Main Authors: Yamanaka, Hitoki, Hoyt, Teri, Bowen, Richard, Yang, Xinghong, Crist, Kathryn, Golden, Sarah, Maddaloni, Massimo, Pascual, David W.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628569/
https://ncbi.nlm.nih.gov/pubmed/18955097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.10.021
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