NF-κB-induced oxidative stress contributes to mitochondrial and cardiac dysfunction in type II diabetes

AIMS: Inflammatory molecules and their transcription factor, nuclear factor kappa-B (NF-κB), are thought to play important roles in diabetes-induced cardiac dysfunction. Here, we investigated the effects of pyrrolidine dithiocarbamate (PDTC), a NF-κB inhibitor, in diabetic mice. METHODS AND RESULTS:...

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Bibliografiske detaljer
Main Authors:	Mariappan, Nithya, Elks, Carrie M., Sriramula, Srinivas, Guggilam, Anuradha, Liu, Zhizhen, Borkhsenious, Olga, Francis, Joseph
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 2010
Fag:	Original Articles
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2860708/ https://ncbi.nlm.nih.gov/pubmed/19729361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp305
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NF-κB-induced oxidative stress contributes to mitochondrial and cardiac dysfunction in type II diabetes

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