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Peripheral endothelin B receptor agonist-induced antinociception involves endogenous opioids in mice

Endothelin-1 (ET-1) produced by various cancers is known to be responsible for inducing pain. While ET-1 binding to ETAR on peripheral nerves clearly mediates nociception, effects from binding to ETBR are less clear. The present study assessed the effects of ETBR activation and the role of endogenou...

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Main Authors: Quang, Phuong N., Schmidt, Brian L.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860690/
https://ncbi.nlm.nih.gov/pubmed/20206445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2010.02.009
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