CB(2) cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids

CB(2) cannabinoid receptor-selective agonists are promising candidates for the treatment of pain. CB(2) receptor activation inhibits acute, inflammatory, and neuropathic pain responses but does not cause central nervous system (CNS) effects, consistent with the lack of CB(2) receptors in the normal...

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Main Authors: Ibrahim, Mohab M., Porreca, Frank, Lai, Josephine, Albrecht, Phillip J., Rice, Frank L., Khodorova, Alla, Davar, Gudarz, Makriyannis, Alexandros, Vanderah, Todd W., Mata, Heriberto P., Malan, T. Philip
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2005
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC549497/
https://ncbi.nlm.nih.gov/pubmed/15705714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409888102
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