CB(2) cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids

CB(2) cannabinoid receptor-selective agonists are promising candidates for the treatment of pain. CB(2) receptor activation inhibits acute, inflammatory, and neuropathic pain responses but does not cause central nervous system (CNS) effects, consistent with the lack of CB(2) receptors in the normal...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ibrahim, Mohab M., Porreca, Frank, Lai, Josephine, Albrecht, Phillip J., Rice, Frank L., Khodorova, Alla, Davar, Gudarz, Makriyannis, Alexandros, Vanderah, Todd W., Mata, Heriberto P., Malan, T. Philip
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC549497/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15705714/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0409888102
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