CB(2) cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids

CB(2) cannabinoid receptor-selective agonists are promising candidates for the treatment of pain. CB(2) receptor activation inhibits acute, inflammatory, and neuropathic pain responses but does not cause central nervous system (CNS) effects, consistent with the lack of CB(2) receptors in the normal...

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Bibliografske podrobnosti
Main Authors: Ibrahim, Mohab M., Porreca, Frank, Lai, Josephine, Albrecht, Phillip J., Rice, Frank L., Khodorova, Alla, Davar, Gudarz, Makriyannis, Alexandros, Vanderah, Todd W., Mata, Heriberto P., Malan, T. Philip
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC549497/
https://ncbi.nlm.nih.gov/pubmed/15705714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409888102
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