CB(2) cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids

CB(2) cannabinoid receptor-selective agonists are promising candidates for the treatment of pain. CB(2) receptor activation inhibits acute, inflammatory, and neuropathic pain responses but does not cause central nervous system (CNS) effects, consistent with the lack of CB(2) receptors in the normal...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ibrahim, Mohab M., Porreca, Frank, Lai, Josephine, Albrecht, Phillip J., Rice, Frank L., Khodorova, Alla, Davar, Gudarz, Makriyannis, Alexandros, Vanderah, Todd W., Mata, Heriberto P., Malan, T. Philip
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2005
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC549497/
https://ncbi.nlm.nih.gov/pubmed/15705714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409888102
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