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Methadone antinociception is dependent on peripheral opioid receptors
Morphine and methadone are both high affinity, potent mu opioid peptide (MOP) receptor analgesics. Here we compared the antinociceptive potencies of these two drugs when administered subcutaneously (s.c.), intrathecally (i.t.) or intracerebroventricularly (i.c.v.) in both rat and mouse using the tai...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2952445/ https://ncbi.nlm.nih.gov/pubmed/19327642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2008.09.011 |
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