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Peripheral endothelin B receptor agonist-induced antinociception involves endogenous opioids in mice

Endothelin-1 (ET-1) produced by various cancers is known to be responsible for inducing pain. While ET-1 binding to ETAR on peripheral nerves clearly mediates nociception, effects from binding to ETBR are less clear. The present study assessed the effects of ETBR activation and the role of endogenou...

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Detalhes bibliográficos
Main Authors: Quang, Phuong N., Schmidt, Brian L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860690/
https://ncbi.nlm.nih.gov/pubmed/20206445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2010.02.009
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