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Chemoenzymatic syntheses of prenylated aromatic small molecules using Streptomyces prenyltransferases with relaxed substrate specificities

NphB is a soluble prenyltransferase from Streptomyces sp. strain CL190 that attaches a geranyl group to a 1,3,6,8-tetrahydroxynaphthalene-derived polyketide during the biosynthesis of anti-oxidant naphterpin. Here we report multiple chemoenzymatic syntheses of various prenylated compounds from aroma...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Kumano, Takuto, Richard, Stéphane B., Noel, Joseph P., Nishiyama, Makoto, Kuzuyama, Tomohisa
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860626/
https://ncbi.nlm.nih.gov/pubmed/18682327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.07.052
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