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Caged Protein Prenyltransferase Substrates: Tools for Understanding Protein Prenylation
Originally designed to block the prenylation of oncogenic Ras, inhibitors of protein farnesyltransferase currently in pre-clinical and clinical trials are showing efficacy in cancers with normal Ras. Blocking protein prenylation has also shown promise in the treatment of malaria, Chagas disease, and...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680146/ https://ncbi.nlm.nih.gov/pubmed/18844669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2008.00698.x |
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