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Outside-In Signal Transmission by Conformational Changes in Integrin Mac-1

Intracellular signals associated with or triggered by integrin ligation can control cell survival, differentiation, proliferation, and migration. Despite accumulating evidence that conformational changes regulate integrin affinity to its ligands, how integrin structure regulates signal transmission...

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Detalhes bibliográficos
Main Authors: Lefort, Craig T., Hyun, Young-Min, Schultz, Joanne B., Law, Foon-Yee, Waugh, Richard E., Knauf, Philip A., Kim, Minsoo
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860599/
https://ncbi.nlm.nih.gov/pubmed/19864611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900983
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