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Inhibition of Na(+)/H(+) exchanger enhances low pH-induced L-selectin shedding and β(2)-integrin surface expression in human neutrophils

Ischemia-reperfusion injury is a common pathological occurrence causing tissue damage in heart attack and stroke. Entrapment of neutrophils in the vasculature during ischemic events has been implicated in this process. In this study, we examine the effects that lactacidosis and consequent reductions...

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Detalhes bibliográficos
Main Authors: Kaba, Nubia K., Schultz, Joanne, Law, Foon-Yee, Lefort, Craig T., Martel-Gallegos, Guadalupe, Kim, Minsoo, Waugh, Richard E., Arreola, Jorge, Knauf, Philip A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584992/
https://ncbi.nlm.nih.gov/pubmed/18829897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00535.2007
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