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Activation of human neutrophil Mac-1 by anion substitution *
Substituting the medium chloride with glucuronate or glutamate causes a rapid, 10 to 30 –fold, increase in the binding of the monoclonal antibody, CBRM1/5, which recognizes the high-affinity conformation of the Mac-1 integrin. This change is reflected in functional adhesion assays that show increase...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2671573/ https://ncbi.nlm.nih.gov/pubmed/19246218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2009.01.006 |
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