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Substrate-dependent reversal of anion transport site orientation in the human red blood cell anion-exchange protein, AE1

The tightly coupled, one-for-one exchange of anions mediated by the human red blood cell AE1 anion-exchange protein involves a ping-pong mechanism, in which AE1 alternates between a state with the anion-binding site facing inward toward the cytoplasm (Ei) and a state with the site facing outward tow...

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Detalhes bibliográficos
Main Authors: Knauf, Philip A., Law, Foon-Yee, Leung, Tze-Wah Vivian, Gehret, Austin U., Perez, Martha L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125063/
https://ncbi.nlm.nih.gov/pubmed/12149479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162402399
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