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Substrate-dependent reversal of anion transport site orientation in the human red blood cell anion-exchange protein, AE1

The tightly coupled, one-for-one exchange of anions mediated by the human red blood cell AE1 anion-exchange protein involves a ping-pong mechanism, in which AE1 alternates between a state with the anion-binding site facing inward toward the cytoplasm (Ei) and a state with the site facing outward tow...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Principais autores: Knauf, Philip A., Law, Foon-Yee, Leung, Tze-Wah Vivian, Gehret, Austin U., Perez, Martha L.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2002
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125063/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12149479/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.162402399
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