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Substrate-dependent reversal of anion transport site orientation in the human red blood cell anion-exchange protein, AE1
The tightly coupled, one-for-one exchange of anions mediated by the human red blood cell AE1 anion-exchange protein involves a ping-pong mechanism, in which AE1 alternates between a state with the anion-binding site facing inward toward the cytoplasm (Ei) and a state with the site facing outward tow...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125063/ https://ncbi.nlm.nih.gov/pubmed/12149479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162402399 |
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