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Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution
Bisulfite sequencing measures absolute levels of DNA methylation at single-nucleotide resolution, providing a robust platform for molecular diagnostics. Here, we optimize bisulfite sequencing for genome-scale analysis of clinical samples. Specifically, we outline how restriction digestion targets bi...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860480/ https://ncbi.nlm.nih.gov/pubmed/20062050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1414 |
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