Calcium-Mediated Dual-Mode Regulation of Cardiac Sodium Channel Gating

Intracellular Ca(2+) ([Ca(2+)](i)) can trigger dual-mode regulation of the voltage gated cardiac sodium channel (Na(V)1.5). The channel components of the Ca(2+) regulatory system are the calmodulin (CaM)-binding IQ motif and the Ca(2+) sensing EF hand–like (EFL) motif in the carboxyl terminus of the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Biswas, Subrata, DiSilvestre, Deborah, Tian, Yanli, Halperin, Victoria L., Tomaselli, Gordon F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860428/
https://ncbi.nlm.nih.gov/pubmed/19265034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.193565
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