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Using the deadly μ-conotoxins as probes of voltage-gated sodium channels

μ-Conotoxins (μ-CTX) are potent Na channel inhibitory peptides isolated from the venom of the predatory marine snail Conus geographus. μ-CTXs exert their biological action by physically occluding the ion-conducting pore of voltage-gated Na (Na(v)) channels with a 1:1 stoichiometry in an all-or-none...

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Detalhes bibliográficos
Main Authors: Li, Ronald A., Tomaselli, Gordon F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698010/
https://ncbi.nlm.nih.gov/pubmed/15246758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxicon.2004.03.028
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