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Discovery of Metabolically Stabilized Electronegative Polyacridine-PEG Peptide DNA Open Polyplexes

Cationic condensing peptides and polymers bind electrostatically to DNA to form cationic polyplexes. While many cationic polyplexes are able to achieve in vitro transfection mediated through electrostatic interactions, few have been able to mediate gene transfer in vivo. The present study describes...

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Détails bibliographiques
Auteurs principaux: Fernandez, Christian A., Baumhover, Nicholas J., Anderson, Kevin, Rice, Kevin G.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860281/
https://ncbi.nlm.nih.gov/pubmed/20218669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc900514s
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