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Discovery of Metabolically Stabilized Electronegative Polyacridine-PEG Peptide DNA Open Polyplexes

Cationic condensing peptides and polymers bind electrostatically to DNA to form cationic polyplexes. While many cationic polyplexes are able to achieve in vitro transfection mediated through electrostatic interactions, few have been able to mediate gene transfer in vivo. The present study describes...

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Autors principals: Fernandez, Christian A., Baumhover, Nicholas J., Anderson, Kevin, Rice, Kevin G.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860281/
https://ncbi.nlm.nih.gov/pubmed/20218669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc900514s
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