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Synthesis and In Vitro Testing of New Potent Polyacridine-Melittin Gene Delivery Peptides
The combination of a polyacridine peptide modified with a melittin fusogenic peptide results in a potent gene transfer agent. Polyacridine peptides of the general formula (Acr-X)(n)-Cys were prepared by solid phase peptide synthesis, where Acr is Lys modified on its ε-amine with acridine, X is Arg,...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2813064/ https://ncbi.nlm.nih.gov/pubmed/19968269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc9003124 |
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